It is dangerous to rent a car, charter buses, marked vans therefore, volunteers, missionaries and school groups are often attacked abroad.
I am flying to the Dominican Republic tonight, and I happened to read a Canadian government travel warning about the DR. I then checked the U.S. Department of State Bureau of Consular Affairs information sheets and discovered some travel advice about dangerous situations.
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Situational awareness and security issues change by country, transportation, language, religion and specific neighborhoods, etc.
Safe-travel protocols in one country may be completely different in another. You need to discuss the pros and cons with experienced travel experts.